Dr Otavio Berwanger (MD; PhD) Cardiologist and Clinical EpidemiologistCurrent Position: Director of the Research Institute HCor, Heart Hospital (Hospital do Coraá∆o-HCor), Sao Paulo, BrazilMajor Recent Contributions: Created a Network of 154 Cardiovascular Research Sites in Brazil and 20 sites in Latin America. Built the largest Clinical Trials Unit in South America (Research Institute HCor-Heart Hospital) in Sao Paulo-SP, Brazil. Main presenter of the first large trials entirely designed and coordinated by Brazil ever presented during Late-Breaking Clinical Trials sessions (ACT Trial- American Heart Association Scientific Sessions 2010 and BRIDGE-ACS Trial- American College of Cardiology Scientific Sessions 2012). . Founding Member of the Brazilian Network for Health Technology Assessment (REBRATS)- Ministry of Health, Brazil. Chair of the Steering Committee of large-scale clinical trials that were published in major medical journals such as JAMA, NEJM and Circulation. Invited Speaker at major international events such as (including: American Heart Association Scientific Sessions, American College of Cardiology Scientific Sessions, European Society of Cardiology Congress, Society of Clinical Trials, Cochrane Symposium).