Dr. Kuku is a Master Physician and Endocrinologist, renowned Scholar and Administrator. He holds several degrees and Fellowships in medicine, including two doctorates. He has been the Joint Chief Medical Director and Co-Chairman at the EKO Hospital (Ekocorp Pic) which he co­founded in 1978.

Dr. Kuku has also been a Trustee and a Distinguished Fellow of the National Postgraduate Medical College of Nigeria, President and Trustee West African College of Physicians,President of the Pan African diabetes Study Group, and President of the Nigerian NCD Alliance.

He also was Chairman of the Committee of Pro-Chancellors of State Universities and Committee of Chairmen of Federal Tertiary Hospitals, the first African Honorary Fellow of the Colleges of Physicians of South Africa and Glasgow, and holds an Honorary DSc Ed (TAUSED).

Dr. Kuku is a Fellow of the Nigerian Academy of Science, and was awarded the National Honour of the Officer of the Order of the Federal Republic of Nigeria (OFR) in 2003.  He was Chairman of Ecobank Nigeria, and the Chairman of the Human Capital Policy Commission of the Nigerian Economic Summit Group.  He became the first African Master of the American College of Physicians in 2005, Honorary Life President of the Nigerian Society of Endocrinology, and Honorary Life Patron of the Diabetes Association of Nigeria.

He is Chairman Clina-Lancet Laboratories and Director of Total Health Trust Ltd among others.

A widely cited author (including Who is Who in the World),he holds several traditional titles including the hereditary Olor'ogun  of ljebu-ode. He is the Founder of The Sonny Kuku Foundation.